The use of fluor-hydroxy pulse peel in actinic porokeratosis.

Abstract

BACKGROUND:

The use of Fluor-Hydroxy pulse peel (Drogaderma, Sao Paulo, Brazil) was reported by Katz to treat solar damage and actinic keratosis-associated lesions.

OBJECTIVE:

The objective was to use this combined treatment to produce therapeutic and cosmetic benefits in a patient with actinic porokeratosis.

METHODS:

A case of actinic disseminated porokeratosis was treated with a combination of a 70% glycolic peel and a 5% 5-fluorouracil solution (Drogaderma) every 2 weeks for 4 months. A biopsy was done before and after eight treatment pulses.

RESULTS:

Improvement in the appearance and texture of the treated areas and decreased dyskeratosis and epidermal atypia.

CONCLUSION:

The Fluor-Hydroxy pulse peel can be an effective alternative for the treatment of actinic porokeratosis.

• Authors: Solange P Teixeira, Maurício M de Nascimento, Ediléia Bagatin, Karime M Hassun, Sérgio Talarico, Nilceo Michalany
• Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 31 Issue 9 Pt 1 Pg. 1145-8 (Sep 2005) ISSN: 1076-0512 [Print] United States
• PMID: 16164867 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glycolates
• Keratolytic Agents
• glycolic acid
• Fluorouracil

Topics

• Biopsy
• Chemexfoliation (methods)
• Female
• Fluorouracil (therapeutic use)
• Glycolates (therapeutic use)
• Humans
• Keratolytic Agents (therapeutic use)
• Middle Aged
• Porokeratosis (drug therapy, etiology)
• Skin (pathology)
• Ultraviolet Rays (adverse effects)