Abstract | BACKGROUND AND OBJECTIVES: METHODS: Animals were randomly divided into six groups (n = 6 in each group), a sham-operated group, an operated group without infusion, and 4 operated groups with infusion (BRS, ARS, LRS and RS groups). Each RS was intravenously administered at 60 mL kg(-1) h(-1) for 1.5 h. Arterial blood gases, plasma electrolytes and cardiovascular parameters were analysed. RESULTS: BRS significantly improved blood base excess values, which were decreased by blood-letting, faster and more markedly than did LRS and RS (BRS--6.3 +/- 0.5 mEq L(-1); LRS--9.2 +/- 1.1 mEq L(-1); RS--12.4 +/- 1.0 mEq L(-1) at the end of infusion). The alkalinizing effect of BRS tended to be better than that of ARS but not significantly so. The serum Mg2+ concentration was well-maintained by BRS as compared to other RS (BRS 1.5 +/- 0.0 mgdL(-1); ARS 1.2 +/- 0.0mgdL(-1); LRS 1.1 +/- 0.0mgdL(-1); RS 1.3 +/- 0.1 mgdL(-1), at the end of infusion). CONCLUSIONS: These results suggest that BRS is a suitable perioperative solution for metabolic acidosis and serum electrolyte balance among RS tested.
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Authors | K Satoh, M Ohtawa, M Katoh, E Okamura, T Satoh, A Matsuura, Y Oi, R Ogawa |
Journal | European journal of anaesthesiology
(Eur J Anaesthesiol)
Vol. 22
Issue 9
Pg. 703-11
(Sep 2005)
ISSN: 0265-0215 [Print] England |
PMID | 16163918
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Hemoglobins
- Isotonic Solutions
- Ringer's Lactate
- Ringer's acetate
- bicarbonated Ringer's solution
- Carbon Dioxide
- Lactic Acid
- Ringer's Solution
- Sodium Bicarbonate
- Magnesium
- Oxygen
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Topics |
- Acid-Base Equilibrium
(drug effects)
- Acidosis
(blood, therapy)
- Animals
- Blood Pressure
(physiology)
- Carbon Dioxide
(blood)
- Disease Models, Animal
- Dogs
- Heart Rate
(physiology)
- Hematocrit
- Hemoglobins
(analysis)
- Hemorrhage
(complications)
- Infusions, Intravenous
- Isotonic Solutions
(therapeutic use)
- Lactic Acid
(blood)
- Magnesium
(blood, therapeutic use)
- Male
- Oxygen
(blood)
- Random Allocation
- Ringer's Lactate
- Ringer's Solution
- Shock
(physiopathology, therapy)
- Sodium Bicarbonate
(therapeutic use)
- Time Factors
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