Abstract | BACKGROUND: The potent anti-inflammatory pharmacologic effects of the corticosteroids ( cortisone and synthetic derivatives) has led to their extensive usage in the management of rheumatologic diseases and athletic musculoskeletal injuries. The efficacy and risks of locally injected or systemically administered corticosteroids in the treatment of athletic injuries are unclear. OBJECTIVE: DATA SOURCES: A search of 3 databases-MEDLINE, CINAHL, and Cochrane Clinical Trial Register-was performed using the OVID interface for all years between 1966 and 2003. The search first combined all references under the medical subject headings adrenal cortex hormones, glucocorticoids, and glucocorticoids, synthetic. A second search combined all references under the medical subject headings athletic injuries, sprains and strains, tendon injuries, shoulder injuries, rotator cuff disease, tennis elbow, and lateral epicondylitis. The references identified by these 2 searches were intersected and limited to human only to produce 130 articles. Relevant review articles were scanned, references reviewed, and additional articles retrieved for consideration of inclusion. STUDY SELECTION: For inclusion in this critical review, articles must meet the following criteria: (1) subjects were human, (2) subjects had athletic-related injuries, and (3) subjects received corticosteroid treatment. Ultimately, 43 studies met inclusion criteria. DATA EXTRACTION AND SYNTHESIS: MAIN RESULTS: CONCLUSIONS:
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Authors | Andrew W Nichols |
Journal | Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
(Clin J Sport Med)
Vol. 15
Issue 5
Pg. 370-5
(Sep 2005)
ISSN: 1050-642X [Print] United States |
PMID | 16162982
(Publication Type: Journal Article, Review)
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Chemical References |
- Adrenal Cortex Hormones
- Glucocorticoids
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Topics |
- Administration, Oral
- Adrenal Cortex Hormones
(adverse effects, therapeutic use)
- Athletic Injuries
(drug therapy)
- Glucocorticoids
(adverse effects, therapeutic use)
- Humans
- Injections, Intra-Articular
- Pain
(etiology)
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