Abstract | BACKGROUND: METHODS: In 2 separate 3-week studies of similar design, pain intensity, pain relief, length of hospital stay, analgesic use and side effects of CR oxycodone (n = 70) and ST (n = 101) were evaluated. In the CR oxycodone trial, a dose de-escalation protocol was used. RESULTS: CONCLUSIONS: CR oxycodone every 12 hours is as effective as ST in treating postoperative pain but length of hospital stay was shorter and analgesic administration in the hospital was used less frequently, providing potential hospital cost savings and reduced use of health care resources.
|
Authors | Justin de V de Beer, Mitchell J Winemaker, Graeme A E Donnelly, Paula C Miceli, Joseph L Reiz, Zoltan Harsanyi, Lance W Payne, Andrew C Darke |
Journal | Canadian journal of surgery. Journal canadien de chirurgie
(Can J Surg)
Vol. 48
Issue 4
Pg. 277-83
(Aug 2005)
ISSN: 0008-428X [Print] Canada |
PMID | 16149361
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Analgesics
- Analgesics, Opioid
- Delayed-Action Preparations
- Oxycodone
|
Topics |
- Aged
- Analgesics
(therapeutic use)
- Analgesics, Opioid
(therapeutic use)
- Arthroplasty, Replacement
(adverse effects)
- Delayed-Action Preparations
- Female
- Humans
- Male
- Middle Aged
- Osteoarthritis
(surgery)
- Oxycodone
(therapeutic use)
- Pain Measurement
- Pain, Postoperative
(drug therapy, etiology)
- Treatment Outcome
|