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Syscan3, a kit for detection of anti-Candida antibodies for diagnosis of invasive candidiasis.

Abstract
Sera from 76 immunocompetent and 293 immunocompromised subjects were assayed for anti-Candida antibodies. The sensitivity, specificity, positive predictive value, and negative predictive value for invasive candidiasis were 74%, 75%, 62%, and 84% in the immunocompetent group and 15%, 60%, 1.7%, and 93% in the immunocompromised group, respectively. Syscan3 has high negative predictive value.
AuthorsAnnie Philip, Zekaver Odabasi, Gloria Matiuzzi, Victor L Paetznick, Sze-Wee Tan, John Warmington, John H Rex, Luis Ostrosky-Zeichner
JournalJournal of clinical microbiology (J Clin Microbiol) Vol. 43 Issue 9 Pg. 4834-5 (Sep 2005) ISSN: 0095-1137 [Print] United States
PMID16145152 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antibodies, Fungal
  • Antigens, Fungal
  • Reagent Kits, Diagnostic
Topics
  • Antibodies, Fungal (blood)
  • Antigens, Fungal (immunology)
  • Candida (classification, immunology)
  • Candidiasis (diagnosis, microbiology)
  • Enzyme-Linked Immunosorbent Assay (methods)
  • Fungemia (diagnosis, microbiology)
  • Humans
  • Immunocompetence
  • Immunocompromised Host
  • Predictive Value of Tests
  • Reagent Kits, Diagnostic
  • Sensitivity and Specificity

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