Abstract |
Sera from 76 immunocompetent and 293 immunocompromised subjects were assayed for anti-Candida antibodies. The sensitivity, specificity, positive predictive value, and negative predictive value for invasive candidiasis were 74%, 75%, 62%, and 84% in the immunocompetent group and 15%, 60%, 1.7%, and 93% in the immunocompromised group, respectively. Syscan3 has high negative predictive value.
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Authors | Annie Philip, Zekaver Odabasi, Gloria Matiuzzi, Victor L Paetznick, Sze-Wee Tan, John Warmington, John H Rex, Luis Ostrosky-Zeichner |
Journal | Journal of clinical microbiology
(J Clin Microbiol)
Vol. 43
Issue 9
Pg. 4834-5
(Sep 2005)
ISSN: 0095-1137 [Print] United States |
PMID | 16145152
(Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antibodies, Fungal
- Antigens, Fungal
- Reagent Kits, Diagnostic
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Topics |
- Antibodies, Fungal
(blood)
- Antigens, Fungal
(immunology)
- Candida
(classification, immunology)
- Candidiasis
(diagnosis, microbiology)
- Enzyme-Linked Immunosorbent Assay
(methods)
- Fungemia
(diagnosis, microbiology)
- Humans
- Immunocompetence
- Immunocompromised Host
- Predictive Value of Tests
- Reagent Kits, Diagnostic
- Sensitivity and Specificity
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