Indocyanine green angiography of juvenile X-linked retinoschisis.

Abstract

PURPOSE:

In juvenile X-linked retinoschisis (XLRS), fluorescein angiography is usually unremarkable and contributes poorly to the diagnosis. However, indocyanine green (ICG) angiography features in eyes that are affected with XLRS were not yet described.

DESIGN:

Retrospective observational case series.

METHODS:

A complete ophthalmologic examination that included ICG angiography was performed on three unrelated male patients (six eyes) who were 15, 22, and 48 years old.

RESULTS:

A distinct hyperfluorescent stellate pattern in the macular area that was associated with radial lines of hypofluorescence that were centered on the foveola was observed on the early phase of ICG examination (six of six eyes). This feature disappeared on the late phase of ICG examination.

CONCLUSION:

On these six XLRS eyes, early phases of ICG examination revealed an unusual radial aspect on the macula. This finding suggests that ICG angiography may be useful for the diagnosis of XLRS.

• Authors: Eric H Souied, Anna Goritsa, Giuseppe Querques, Gabriel Coscas, Gisele Soubrane
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 140 Issue 3 Pg. 558-61 (Sep 2005) ISSN: 0002-9394 [Print] United States
• PMID: 16139020 (Publication Type: Case Reports, Journal Article)

Chemical References

• Coloring Agents
• Indocyanine Green

Topics

• Adolescent
• Adult
• Coloring Agents
• Fluorescein Angiography
• Humans
• Indocyanine Green
• Male
• Middle Aged
• Retina (pathology)
• Retinoschisis (diagnosis)
• Retrospective Studies