| Abstract | PURPOSE: To evaluate the prevalence of latent and manifest hyperthyroidism in a non-selected group of patients admitted for contrast enhanced CT studies blood samples were tested for the levels of thyroid-stimulating hormone (TSH). MATERIAL AND METHODS: TSH blood levels were obtained in 548 consecutive patients who were scheduled for contrast-enhanced (Iopromide; 300 mg iodine/ml) CT scanning. In case of TSH levels < 0.4 mU/l, blood samples were also tested for triiodothyronine (T3) and tetraiodothyronine (T4) blood levels, and treatment with Irenat (sodium perchlorate) was commenced before scanning. In case of TSH levels < 0.1 mU/l, CT scanning was not performed but further evaluation of the thyroid function was initiated. RESULTS: TSH blood levels ranged from 0.4 to 7.5 mU/l in 512 patients, and 36 patients (6.6%) had TSH blood levels < 0.4 mU/l and 9 patients blood levels < 0.1 mU/l, with 32 of those patients (5.8%) having regular T3 and T4 blood levels consistent with latent hyperthyroidism. In 4 patients (0.8%), T3 or T4 blood levels were increased consistent with manifest hyperthyroidism. CONCLUSION: In South Germany, the prevalence of latent or manifest hyperthyroidism in a non-selected patient group is high. Therefore TSH blood levels should be obtained prior to contrast-enhanced CT studies. |
| Authors | T Saam, T Hess, C Kasperk, G W Kauffmann, M Düx
(Affiliation: Universitätsklinikum Heidelberg, Abteilung Radiodiagnostik, Heidelberg. saamt at u.washington.edu)
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| Journal | RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
(Rofo)
Vol. 177
Issue 9
Pg. 1250-4
(Sep 2005)
ISSN: 1438-9029 Germany |
| Vernacular Title | Prävalenz der latenten und manifesten Hyperthyreose in einem Jodmangelgebiet: Erhebung an einem nichtselektionierten Patientenkollektiv vor Durchführung einer Computertomographie mit jodhaltigem Kontrastmittel. |
| PMID | 16123871
(Publication Type: Comparative Study, English Abstract, Evaluation Studies, Journal Article)
|
| Chemical References |
- Contrast Media
- Sodium Compounds
- Iohexol
- Triiodothyronine
- iopromide
- Thyroxine
- sodium perchlorate
- Perchloric Acid
- Thyrotropin
|
| Topics |
- Adult
- Aged
- Aged, 80 and over
- Contrast Media
- Germany
(epidemiology)
- Humans
- Hyperthyroidism
(blood, epidemiology)
- Iohexol
(analogs & derivatives, diagnostic use)
- Middle Aged
- Perchloric Acid
(administration & dosage)
- Prevalence
- Sodium Compounds
(administration & dosage)
- Thyrotropin
(blood)
- Thyroxine
(blood)
- Tomography, X-Ray Computed
- Triiodothyronine
(blood)
|
