Abstract |
We describe an anal disease activity index suitable for use in prospective studies of treatment and recording the natural history of anal disease. We studied 40 patients with perianal Crohn's disease ( PACD), 14 patients with anal disease not related to Crohn's disease, and 10 normal individuals. Seven symptoms related to anal disease were measured using a linear analog scoring system, which proved easy for the patients to complete. Only three of the seven clinical parameters studied before and after treatment had a high discriminant value. On the basis of these findings, we conclude that a good index of response to therapy in patients with anal disease can be obtained from a linear analog scoring of three symptoms: spontaneous anal pain, pain following defecation, and inhibition of locomotion by pain. The index should be of value in comparing management options in PACD.
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Authors | A Allan, L Linares, H A Spooner, J Alexander-Williams |
Journal | Diseases of the colon and rectum
(Dis Colon Rectum)
Vol. 35
Issue 7
Pg. 656-61
(Jul 1992)
ISSN: 0012-3706 [Print] United States |
PMID | 1611953
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Anus Diseases
(complications, diagnosis, surgery)
- Crohn Disease
(complications, diagnosis)
- Female
- Humans
- Male
- Middle Aged
- Reference Values
- Severity of Illness Index
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