HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Nebulizers or pressurized metered-dose inhalers in the treatment of asthma exacerbations.

Abstract
The use of inhaled beta2-agonists delivered by a metered-dose inhaler (MDI) with a holding chamber (spacer) actually is considered the best treatment for childhood acute asthma. However, its use in daily practice still seems rather limited. The aim of this study was to investigate, using a questionnaire, the use of a nebulizer or MDI as the first-line method for delivering inhaled beta2-agonists in children with acute asthma. A questionnaire was developed and distributed to 22 pediatric departments and to 131 family pediatricians (FPs) in northeast Italy. We showed that in the hospitals the episodes of acute asthma usually were treated with bronchodilators administered by wet nebulization (95.45%). This was the case also for FPs (70.9%). However, 29.1% of FPs usually advised the use of an MDI/holding chamber to children with acute asthma. Despite the established efficacy of inhaled beta2-agonists administrated with an MDI compared with wet nebulization in acute asthma, this practice still is rather limited. The use of wet nebulization was more evident in hospital settings compared with community medicine. Emergency room visits may represent a missed opportunity to promote an effective method of delivering bronchodilators in childhood asthma.
AuthorsDaniele Radzik, Diego G Peroni, Lydia Pescollderungg, Giorgio L Piacentini, Atanasio Chatzimichail, Attilio L Boner
JournalAllergy and asthma proceedings (Allergy Asthma Proc) 2005 May-Jun Vol. 26 Issue 3 Pg. 207-9 ISSN: 1088-5412 [Print] United States
PMID16119036 (Publication Type: Journal Article)
Chemical References
  • Adrenergic beta-Agonists
  • Bronchodilator Agents
Topics
  • Acute Disease
  • Administration, Inhalation
  • Adrenergic beta-Agonists (administration & dosage)
  • Asthma (drug therapy)
  • Attitude of Health Personnel
  • Bronchodilator Agents (administration & dosage)
  • Child
  • Clinical Competence
  • Emergency Service, Hospital
  • Health Care Surveys
  • Humans
  • Inhalation Spacers (statistics & numerical data)
  • Italy
  • Physicians (psychology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: