LY-544344. Eli Lilly.

Abstract

Eli Lilly and Co is developing LY-544344, a prodrug of the metabotropic glutamate receptor 2/3 agonist LY-354740, for the potential treatment of anxiety disorders.

• Authors: Wojciech Danysz
• Journal: IDrugs : the investigational drugs journal (IDrugs) Vol. 8 Issue 9 Pg. 755-62 (Sep 2005) ISSN: 1369-7056 [Print] England
• PMID: 16118698 (Publication Type: Journal Article, Review)

Chemical References

• 2-((2'-amino)propionyl)aminobicyclo(3.1.0)hexane-2,6-dicarboxylic acid
• Anti-Anxiety Agents
• Bridged Bicyclo Compounds
• Prodrugs
• Receptors, Metabotropic Glutamate
• metabotropic glutamate receptor 2
• metabotropic glutamate receptor 3
• Alanine
• eglumetad

Topics

• Alanine (analogs & derivatives)
• Animals
• Anti-Anxiety Agents (chemical synthesis, metabolism, pharmacology, therapeutic use)
• Anxiety (drug therapy)
• Bridged Bicyclo Compounds (chemical synthesis, metabolism, pharmacology, therapeutic use)
• Clinical Trials as Topic
• Humans
• Prodrugs (therapeutic use)
• Receptors, Metabotropic Glutamate (agonists)
• Structure-Activity Relationship