[Gamma-scintigraphy with Ga-67 citrate in differential diagnosis of residual tumors in lymphogranulomatosis and lymphosarcoma].

Abstract

AIM:

To study informative and diagnostic efficacy of quantitative evaluation of the results of gamma-scintigraphy in patients with lymphogranulomatosis and lymphosarcoma with prevalent mediastinal and pulmonary lesions.

MATERIAL AND METHODS:

100 patients with verified lymphogranulematosis were studied: 67 with lymphosarcoma and 33 with mediastinal involvement. The mediastinal tumor monitoring was made before therapy, in complete clinicohematological remission, in progression using a complex of radio-, clinicohematological, histomorphological and radionuclide methods.

RESULTS:

A comparative analysis of the findings of radiation, radionuclide and histomorphological examinations of the removed residual mediastinal tumor in 10 patients showed that scintigraphic evidence was similar to that of histological findings in most of the examinees.

CONCLUSION:

A high diagnostic efficacy of a complex of radiation and radionuclide methods with Ga-67 citrate based on estimation of accumulation intensity providing comprehensive information about mediastinal tumor is demonstrated. A comparative analysis was made of the results of radiation, radionuclide and histomorphological examinations of the removed residual lesion of the mediastinum in 10 patients. In most cases, scintigraphic findings coincided with the results of histological studies of biopsies of mediastinal residual lesion.

• Authors: E D Iskhakov, Ia D Sakhibov, N Sh Sagdieva, I B Kaplanskaia, B T Dzhumabaeva, V S Shavlokhov, S K Kravchenko, L N Gotman, A A Shevelev
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 77 Issue 7 Pg. 61-4 ( 2005) ISSN: 0040-3660 [Print] Russia (Federation)
• PMID: 16116912 (Publication Type: Comparative Study, Evaluation Study, Journal Article)

Chemical References

• Citrates
• Radiopharmaceuticals
• Gallium
• gallium citrate

Topics

• Adolescent
• Adult
• Biopsy
• Citrates
• Diagnosis, Differential
• Female
• Gallium
• Gamma Rays
• Hodgkin Disease (diagnostic imaging, pathology)
• Humans
• Lymphoma, Non-Hodgkin (diagnostic imaging, pathology)
• Male
• Mediastinum
• Middle Aged
• Neoplasm, Residual
• Radionuclide Imaging
• Radiopharmaceuticals
• Reproducibility of Results
• Sensitivity and Specificity