[Biological alcohol markers. Genetic markers for familial alcoholism and markers for the detection of harmful alcohol consumption].

Abstract

Existing biological markers of alcoholism and excessive alcohol consumption are of poor sensitivity and specificity, and new, improved markers are needed. Owing to the genetic contribution to the development of alcoholism, as demonstrated in family and adoption studies, a search has been initiated for 'preventive' or genetic markers. In addition, other new biochemical markers have been introduced, and results so far obtained with CDT (carbohydrate deficient transferrin) in the detection of alcoholics have been promising. However, the clinical and scientific implications of these new markers need to be elucidated in greater detail.

• Authors: O Nilssen, N E Huseby
• Journal: Nordisk medicin (Nord Med) Vol. 107 Issue 6-7 Pg. 175-6 ( 1992) ISSN: 0029-1420 [Print] Sweden
• Vernacular Title: Biologiske alkoholmarkører. Genetiske markører for familioer alkoholisme og markører for påvisning av skadelig alkoholkonsum.
• PMID: 1608743 (Publication Type: English Abstract, Journal Article)

Chemical References

• Biomarkers
• Genetic Markers
• Transferrin
• carbohydrate-deficient transferrin
• Alcohol Dehydrogenase
• Aldehyde Dehydrogenase
• Monoamine Oxidase
• Aspartate Aminotransferases
• Hexosaminidases
• Adenylyl Cyclases

Topics

• Adenylyl Cyclases (blood)
• Alcohol Dehydrogenase (blood)
• Alcoholism (diagnosis, enzymology, genetics)
• Aldehyde Dehydrogenase (blood)
• Aspartate Aminotransferases (analysis)
• Biomarkers (blood)
• Electroencephalography
• Genetic Markers
• Hexosaminidases (blood)
• Humans
• Monoamine Oxidase (blood)
• Risk Factors
• Transferrin (analogs & derivatives, analysis)