Abstract | OBJECTIVES:
Langerhans cell histiocytosis is a proliferating cell disease that may take various forms characterised by bone, skin lymph nodes and visceral lesions. Eosinophilic granuloma is a localised form of histiocytosis X, or Langerhans' cells histiocytosis, a benign form with unknown aetiology. At the head and neck level, it is usually located on the temporal, and usually occur in association with multifocal disease; however, isolated lesions may occur in the mastoid bone alone. METHODS: RESULTS: CT scan demonstrated an osteolytic lesion of the mastoid. The biopsy and immunohistochemical study confirmed the diagnosis. A surgery followed by a radiotherapy (20 Gy) have stabilised the situation. There is no recurrency after one year. CONCLUSION: Unifocal eosinophilic granuloma of the temporal bone is a benign lesion of langerhans' cell histiocytosis. Its diagnosis is difficult when the disease remains isolated. Its treatment depend on its extension and its risks. The excellent prognosis does not dispense on regulary follow up.
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Authors | A Filali Adib, A Lazrak, M Boulaich, N Nazih, A Oujilal, M Kzadri |
Journal | Revue de laryngologie - otologie - rhinologie
(Rev Laryngol Otol Rhinol (Bord))
Vol. 126
Issue 1
Pg. 37-41
( 2005)
ISSN: 0035-1334 [Print] France |
Vernacular Title | Le granulome éosinophile de la mastoïde: à propos d'un cas. |
PMID | 16080647
(Publication Type: Case Reports, English Abstract, Journal Article)
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Topics |
- Adolescent
- Biopsy
- Bone Diseases
(diagnosis)
- Eosinophilic Granuloma
(diagnosis)
- Female
- Follow-Up Studies
- Humans
- Immunohistochemistry
- Mastoid
(pathology)
- Osteolysis
(diagnosis)
- Temporal Bone
(pathology)
- Tomography, X-Ray Computed
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