Abstract | BACKGROUND: METHOD: A retrospective review of 63 major depression patients and 33 adjustment disorder patients in a primary care setting was undertaken. Patients had been prescribed mostly SSRIs. DSM-IV symptoms, PHQ-9 depression rating scale scores, and functional disability reports were systematically used to evaluate partial and full remission from patients' depressive states. RESULTS: Neither depressed patients, nor adjustment disordered patients demonstrated a difference in clinical response to any particular antidepressant. The main statistical difference was in response rates, where patients diagnosed with adjustment disorder were twice as likely to respond to standard antidepressant treatment as depressed patients. This retrospective database design with moderate sample size limits the statistical power of this study. CONCLUSION:
Antidepressants are very effective in treating depression in the primary care setting and may even be an effective and efficient treatment for adjustment disorder with depressed mood.
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Authors | Usman Hameed, Thomas L Schwartz, Kamna Malhotra, Rebecca L West, Francesca Bertone |
Journal | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists
(Ann Clin Psychiatry)
2005 Apr-Jun
Vol. 17
Issue 2
Pg. 77-81
ISSN: 1040-1237 [Print] United States |
PMID | 16075660
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adjustment Disorders
(drug therapy)
- Affect
- Antidepressive Agents
(therapeutic use)
- Cohort Studies
- Depressive Disorder, Major
(drug therapy)
- Female
- Humans
- Male
- Middle Aged
- Primary Health Care
- Retrospective Studies
- Treatment Outcome
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