Bowen disease of the eyelid successfully treated with imiquimod.

Abstract

We present a case of Bowen disease affecting the eyelid that was successfully treated with imiquimod. The clinical presentation, histopathology, and treatment of this case are presented. The tumor was treated with imiquimod for 3 months, leading to complete resolution of the disease both clinically and histopathologically. There was no evidence of recurrence 5 months after treatment cessation. Imiquimod was safely used on the eyelid in this case and may avoid extensive periocular tumor excision and reconstruction in Bowen disease.

• Authors: Paul A Brannan, Heidi K Anderson, Robert C Kersten, Dwight R Kulwin
• Journal: Ophthalmic plastic and reconstructive surgery (Ophthalmic Plast Reconstr Surg) Vol. 21 Issue 4 Pg. 321-2 (Jul 2005) ISSN: 0740-9303 [Print] United States
• PMID: 16052154 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Aminoquinolines
• Antineoplastic Agents
• Ointments
• Imiquimod

Topics

• Administration, Topical
• Aged
• Aminoquinolines (therapeutic use)
• Antineoplastic Agents (therapeutic use)
• Bowen's Disease (drug therapy, pathology)
• Eyelid Neoplasms (drug therapy, pathology)
• Humans
• Imiquimod
• Male
• Ointments
• Skin Neoplasms (drug therapy, pathology)