Abstract | PURPOSE: DATA SOURCES: Selected published clinical trials. CONCLUSIONS: NP, who are ideally placed to successfully manage the majority of patients with SAR, should be fully aware of the treatment options available. Although first-generation over-the-counter antihistamines are convenient to use and are readily accessible, patients run the risk of experiencing adverse effects, such as sedation. For this reason, second-generation antihistamines should be considered a better alternative; however, they need to be evaluated individually on the basis of their proven efficacy and safety. Both cetirizine and fexofenadine are equally effective at relieving the symptoms of SAR; however, cetirizine has been shown to be more likely to cause sedation and impairment. IMPLICATIONS FOR PRACTICE:
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Authors | Kathleen Conboy-Ellis |
Journal | Journal of the American Academy of Nurse Practitioners
(J Am Acad Nurse Pract)
Vol. 17
Issue 8
Pg. 295-301
(Aug 2005)
ISSN: 1041-2972 [Print] United States |
PMID | 16045589
(Publication Type: Journal Article, Review)
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Chemical References |
- Histamine H1 Antagonists
- Histamine H1 Antagonists, Non-Sedating
- Loratadine
- Terfenadine
- fexofenadine
- desloratadine
- Cetirizine
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Topics |
- Adolescent
- Adult
- Cetirizine
(therapeutic use)
- Child
- Child, Preschool
- Histamine H1 Antagonists
(therapeutic use)
- Histamine H1 Antagonists, Non-Sedating
(therapeutic use)
- Humans
- Loratadine
(analogs & derivatives, therapeutic use)
- Nurse Practitioners
- Rhinitis, Allergic, Seasonal
(drug therapy)
- Terfenadine
(analogs & derivatives, therapeutic use)
- Treatment Outcome
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