Contact vitiligo following a strong patch test reaction to triglycidyl-p-aminophenol in an aircraft industry worker: case report and review of the literature.

Abstract

Epoxy resin systems (ERSs) are a frequent cause of occupational allergic contact dermatitis. A 50-year-old patient developed eczematous skin lesions on the back of his hands, lower arms and eye lids, 2 months after he had started working in aircraft construction. Patch tests showed positive reactions at day 3 to nickel sulfate, epoxy resin based on diglycidyl ether of bisphenol F (DGEBF) and 1,4-butanediol diglycidyl ether (1,4-BDDGE). The chemical triglycidyl-p-aminophenol (TGPAP) applied at 1% and 0.1% induced the strongest (+++ positive) reaction. About 4 months after the patch test with TGPAP, the patient presented with 2 circular depigmented spots in the former TGPAP-patch test areas. Dermatohistopathology confirmed the diagnosis of contact vitiligo.

• Authors: U Jappe, J Geier, B M Hausen
• Journal: Contact dermatitis (Contact Dermatitis) Vol. 53 Issue 2 Pg. 89-92 (Aug 2005) ISSN: 0105-1873 [Print] England
• PMID: 16033402 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Aminophenols
• Epoxy Compounds
• triglycidyl-p-aminophenol

Topics

• Aircraft
• Aminophenols (toxicity)
• Dermatitis, Occupational (etiology)
• Epoxy Compounds (toxicity)
• Humans
• Male
• Middle Aged
• Patch Tests
• Vitiligo (chemically induced)