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Effect of active fraction of cerebral on expression of caspase-3 and beta-amyloid precursor protein during therapy of hemorrhagic stroke in the acute and delayed periods.

Abstract
Active anti-stroke fraction of Cerebral preparation (extract of water-soluble molecules from brain tissue of animals with hemorrhagic stroke) decreased caspase-3 expression and improved survival of experimental animals in the acute period after hemorrhagic stroke.
AuthorsA N Makarenko, I G Vasil'eva, N G Chopik, E S Galanta, O I Tsyubko, N P Oleksenko
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 139 Issue 2 Pg. 207-9 (Feb 2005) ISSN: 0007-4888 [Print] United States
PMID16027808 (Publication Type: Journal Article)
Chemical References
  • Amyloid beta-Protein Precursor
  • Caspase Inhibitors
  • Cerebral preparation
  • RNA, Messenger
  • Tissue Extracts
  • Casp3 protein, rat
  • Caspase 3
  • Caspases
Topics
  • Acute Disease
  • Amyloid beta-Protein Precursor (antagonists & inhibitors, genetics, metabolism)
  • Animals
  • Caspase 3
  • Caspase Inhibitors
  • Caspases (genetics, metabolism)
  • Cerebral Hemorrhage (drug therapy, enzymology, metabolism)
  • Male
  • RNA, Messenger (analysis, metabolism)
  • Rats
  • Stroke (drug therapy, enzymology, metabolism)
  • Tissue Extracts (pharmacology, therapeutic use)

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