Characterization of transcription factors and cis-acting elements that regulate human CTP: phosphoethanolamine cytidylyltransferase (Pcyt2).

Abstract	CTP: phosphoethanolamine cytidylyltransferase (Pcyt2) promoter was isolated from human breast cancer MCF-7 cells and its activity delineated by luciferase reporter assays and gel-shift analysis. The Pcyt2 promoter is driven by a functional CAAT box (-90/-73) and by negative (-385/-255) and positive regulatory elements (-255/-153) in the upstream regions.
Authors	Christa M Johnson, Zongfei Yuan, Marica Bakovic
Journal	Biochimica et biophysica acta (Biochim Biophys Acta) Vol. 1735 Issue 3 Pg. 230-5 (Aug 15 2005) ISSN: 0006-3002 [Print] Netherlands
PMID	16023412 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Recombinant Fusion Proteins Recombinant Proteins Transcription Factors RNA Nucleotidyltransferases Ethanolamine-phosphate cytidylyltransferase
Topics	Base Sequence Cloning, Molecular Gene Expression Regulation, Enzymologic Humans Molecular Sequence Data Promoter Regions, Genetic RNA Nucleotidyltransferases (genetics, metabolism) Recombinant Fusion Proteins (metabolism) Recombinant Proteins (metabolism) Regulatory Sequences, Nucleic Acid Sequence Deletion Transcription Factors (metabolism) Transcription, Genetic

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