Treatment of chromoblastomycosis with terbinafine: a report of four cases.

Abstract

This report is about four cases of chromoblastomycosis confirmed by direct examination, histopathology and cultures. The duration of disease infection varied from 5 to 12 years. By culture, Cladosporium carrionii was isolated in two cases and Fonsecaea pedrosoi in the other two cases. Terbinafine 0.25 g twice daily for 1 month and 0.25 g once daily for maintenance therapy were given to three patients. Terbinafine 0.25 g once daily was given to one patient. After 4-8 months of therapy, all cases were cured without relapse when followed up for 6 months. The total dosage of terbinafine was 37.5-60 g. No relevant side effects showed during treatment.

• Authors: Z Xibao, L Changxing, L Quan, H Yuqing
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 16 Issue 2 Pg. 121-4 (Apr 2005) ISSN: 0954-6634 [Print] England
• PMID: 16019628 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Naphthalenes
• Terbinafine

Topics

• Aged
• Antifungal Agents (therapeutic use)
• Chromoblastomycosis (drug therapy, microbiology)
• Cladosporium
• Female
• Humans
• Male
• Middle Aged
• Naphthalenes (therapeutic use)
• Terbinafine