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Hypoprothrombinemia secondary to administration of sulfaquinoxaline to dogs in a kennel setting.

Abstract
Sulfaquinoxaline, a coccidiostat readily available to the public, was mixed in the drinking water for this purpose by the owner. Secondary to its use, a bleeding disorder attributable to hypoprothrombinemia developed in several dogs. Clinical signs of bleeding ceased 24 hours after institution of vitamin K1 and discontinuation of sulfaquinoxaline in the drinking water. This report should remind veterinarians that drugs and medications readily available to the public may have adverse effects in animals, and such problems should be investigated whenever multiple dogs in a common setting are affected with the same clinical problem.
AuthorsT M Neer, R L Savant
JournalJournal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 200 Issue 9 Pg. 1344-5 (May 01 1992) ISSN: 0003-1488 [Print] United States
PMID1601718 (Publication Type: Journal Article)
Chemical References
  • Sulfaquinoxaline
Topics
  • Animals
  • Dog Diseases (chemically induced)
  • Dogs
  • Drinking
  • Female
  • Hypoprothrombinemias (chemically induced, veterinary)
  • Sulfaquinoxaline (administration & dosage, adverse effects)

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