Abstract | BACKGROUND AND OBJECTIVES: METHODS: Eighty-two healthy patients undergoing cesarean delivery with spinal anesthesia were studied. All patients were hydrated with 1500 ml lactated Ringer's solution. Patients were randomly assigned to receive, in a double-blind fashion, 0.2 mg of either morphine (Group 1, n = 40) or saline (Group 2, n = 42) in 0.2 ml volume mixed with 0.75% bupivacaine in 8.25% dextrose plus 0.2 ml 1:1000 epinephrine. Spinal anesthesia was induced using a 25-gauge spinal needle at L3-4 interspace with the bevel, in most cases, parallel to the dural fibers. Patients were followed for three days to evaluate the incidence and severity of headache using a four-category rank scale (none, mild, moderate, severe). Data were analyzed for statistical significance using Student's t-test or chi-square test as appropriate. A p value less than 0.05 was considered significant. Results. The incidence of post dural puncture headache did not differ significantly between groups. Eight patients in Group 1 versus nine patients in Group 2 developed headache (p greater than 0.05). Similarly, the use of blood patch or intravenous caffeine sodium benzoate to treat the headache did not differ significantly between groups. CONCLUSION:
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Authors | T K Abboud, J Zhu, A Reyes, H Miller, Z Steffens, K Afrasiabi, A Afrasiabi, G Sherman, B Emershad |
Journal | Regional anesthesia
(Reg Anesth)
1992 Jan-Feb
Vol. 17
Issue 1
Pg. 34-6
ISSN: 0146-521X [Print] United States |
PMID | 1599892
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Anesthesia, Obstetrical
- Anesthesia, Spinal
- Double-Blind Method
- Female
- Headache
(epidemiology, etiology, prevention & control)
- Humans
- Morphine
(administration & dosage, therapeutic use)
- Pregnancy
- Spinal Puncture
(adverse effects)
- Subarachnoid Space
- United States
(epidemiology)
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