Abstract |
Angiotensin III (Ang III) as well as angiotensin II (Ang II) suppressed body weight loss of the clam worm Perinereis sp. under a hyper-osmotic condition, and enhanced body weight gain under a hypo-osmotic condition. Under a drying condition where the water inflow from outside the body was eliminated, Ang II suppressed body weight loss, but Ang III did not. Under these conditions, angiotensins I, IV, and (1-7) had no effect, and saralasin blocked the effects of Ang II and Ang III. It is concluded that Ang II and Ang III upregulate body fluid volume of the clam worm via Ang II receptors in different ways.
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Authors | Ryousuke Satou, Tsutomu Nakagawa, Hiroki Ido, Masayuki Tomomatsu, Fumiaki Suzuki, Yukio Nakamura |
Journal | Peptides
(Peptides)
Vol. 26
Issue 12
Pg. 2452-7
(Dec 2005)
ISSN: 0196-9781 [Print] United States |
PMID | 15993982
(Publication Type: Journal Article)
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Chemical References |
- Receptor, Angiotensin, Type 2
- Receptors, Angiotensin
- Vasoconstrictor Agents
- Angiotensin II
- Angiotensin III
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Topics |
- Angiotensin II
(metabolism, pharmacology)
- Angiotensin III
(metabolism, pharmacology)
- Animals
- Annelida
(physiology)
- Body Fluids
(metabolism)
- Body Weight
(drug effects)
- Osmosis
(drug effects)
- Receptor, Angiotensin, Type 2
- Receptors, Angiotensin
(metabolism)
- Vasoconstrictor Agents
(pharmacology)
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