HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Biliopancreatic diversion. Clinical experience.

AbstractAIM:
Biliopancreatic diversion (BPD) has been accepted as an effective surgical treatment of morbid obesity. The paper presents the results of a personal clinical experience with this procedure, with special focus on the quality of life.
METHODS:
From January 1, 1992 to June 30, 2002, 122 patients (F/M: 108/14, mean age: 40.2 years, range 21-61) underwent BPD. Mean preoperative body weight was 122.4 kg (range 91-200), with a mean Body Mass Index of 49.1 kg/m2 (range 38-78). Three of these patients were converted from a previous vertical banded gastroplasty to BPD (1 patients with stomach preservation). After at least a 36-month follow-up, 10 patients underwent abdominal dermolipectomy (8 associated to incisional hernia repair, 1 associated to thigh dermolipectomy).
RESULTS:
Mean postoperative hospital stay was 12 days (range: 11-30). Follow-up is currently in progress in all patients. Weight loss of initial overweight was 75% in 88 patients with a 36-month follow-up, with excellent long-term weight maintenance. Protein deficiency was the main specific complication, encountered in 6 patients (4.9%). Beneficial effects, other than those consequent to weight loss, included permanent normalization of serum cholesterol and glucose without any medication and on a totally free diet. Almost 80% of the patients reported an improvement in their self-esteem, physical activity, work condition and social life.
CONCLUSIONS:
This clinical experience supports the effectiveness and safety of BPD, despite some criticism. The small number of side effects and complications, the excellent weight loss and the recovery of most co-morbidity leads to a great improvement in quality of life.
AuthorsG Nanni, G Balduzzi, C Botta, R Capoluongo, P Demichelis, M Scansetti, E Silano
JournalMinerva gastroenterologica e dietologica (Minerva Gastroenterol Dietol) Vol. 51 Issue 2 Pg. 209-12 (Jun 2005) ISSN: 1121-421X [Print] Italy
PMID15990711 (Publication Type: Journal Article)
Topics
  • Adult
  • Biliopancreatic Diversion (adverse effects)
  • Body Mass Index
  • Body Weight
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity, Morbid (psychology, surgery)
  • Protein Deficiency (etiology)
  • Quality of Life
  • Treatment Outcome
  • Weight Loss

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: