Muscular polyarteritis nodosa as a cause of fever of undetermined origin: a case report and review of the literature.

Abstract

We describe an unusual presentation of a localized form of polyarteritis nodosa (PAN) manifested by fever of undetermined origin (FUO). Biopsies of the gastrocnemius muscle revealed necrotizing arteritis and initiation of prednisolone (PSL) brought rapid response. The PAN localized to muscle is rare; furthermore, this disease presented as FUO is very rare. We want to increase awareness that muscle can be also a single-affected site as well as other well known sites such as appendix, gallbladder, uterus or testis, and skin. Since there is no single appellation for this disease, we would like to propose the term "muscular PAN".

• Authors: Takeshi Kamimura, Makio Hatakeyama, Kimiaki Torigoe, Hiroyuki Nara, Naoko Kaneko, Hidetomo Satou, Taku Yoshio, Hitoaki Okazaki, Seiji Minota
• Journal: Rheumatology international (Rheumatol Int) Vol. 25 Issue 5 Pg. 394-7 (Jun 2005) ISSN: 0172-8172 [Print] Germany
• PMID: 15965639 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Glucocorticoids
• Prednisolone

Topics

• Diagnosis, Differential
• Fever of Unknown Origin (etiology)
• Glucocorticoids (therapeutic use)
• Humans
• Male
• Middle Aged
• Muscle, Skeletal (pathology)
• Muscular Diseases (etiology, pathology)
• Polyarteritis Nodosa (complications, drug therapy, pathology)
• Prednisolone (therapeutic use)