Abstract | BACKGROUND: METHODS: A sample of 101 children, ranging in age from 1 to 48 months, was selected, which had presented diarrhea for less than one week from onset, with mild dehydration and no associated complications. Fifty-four children received the ORS/WHO standard treatment, and 47 received a solution with electrolytes similar to ORS/WHO, containing 50 g of precooked plantain flour instead of glucose ( ORS/plantain). RESULTS: Successful rehydration was achieved in 94.4% of the children in the ORS/WHO group and 91.5% in the ORS/plantain group (p = 0.70). Required time for rehydration was 5.8 (SD +/- 3.0) hours in the ORS/WHO group and 6.2 (SD +/- 3.7) hours in the ORS/plantain group (p = 0.31). Stool output during rehydration was 7.5 g/kg body weight/hour (SD +/- 7.6) in the ORS/WHO group, and 7.05 g/kg/hour (SD +/- 9.4) in the ORS/plantain group (p = 0.78). No significant differences were noted in the concentrations of plasma sodium. The observation period was 22.3 hours (SD +/- 5.3) for the ORS/WHO group and 22.7 hours (SD +/- 4.7) for the ORS/plantain group. Stool output during the observation period was 5.7 g/kg/hour (SD +/- 4.7) in the ORS/WHO group and 6.3 g/kg/hour (SD +/- 7.9) in the ORS/plantain group (p = 0.67). The proportion of children requiring intravenous fluids during the first 24 hours was 11.1% in the ORS/WHO group and 8.5% in the ORS/plantain group (RR = 1.31; 95% CI 0.39-4.35). CONCLUSIONS: The plantain flour-based solution proved effective and safe in correcting dehydration; however the antidiarrhoeal properties of ORS/plaintain were not demonstrated.
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Authors | Carlos Bernal, Gloria Margarita Alcaraz, Jorge Eliécer Botero |
Journal | Biomedica : revista del Instituto Nacional de Salud
(Biomedica)
Vol. 25
Issue 1
Pg. 11-21
(Mar 2005)
ISSN: 0120-4157 [Print] Colombia |
Vernacular Title | Hidratación oral con una solución a base de harina de plátano precocida con electrolitos estandarizados. |
PMID | 15962898
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Plant Extracts
- Rehydration Solutions
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Topics |
- Child, Preschool
- Dehydration
(diagnosis, drug therapy, microbiology)
- Diarrhea, Infantile
(diagnosis, drug therapy, microbiology)
- Female
- Flour
- Fluid Therapy
(methods)
- Humans
- Infant
- Male
- Phytotherapy
(methods)
- Plant Extracts
(therapeutic use)
- Plantago
- Rehydration Solutions
(therapeutic use)
- Treatment Outcome
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