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[Treatment with high doses of intravenous immunoglobulin in a case of complicated pemphigus vulgaris]

AbstractA case of a young woman with recalcitrant pemphigus vulgaris involving skin and mucosae, with multiple side effects due to the chronic use of corticosteroids and azathioprine related myelosuppression is presented. She received high doses of intravenous immunoglobulin for five consecutive days and showed a rapid disease control, with healing in three weeks. Remission observed in this patient supports the idea that intravenous immunoglobulin is a good alternative of treatment for patients with pemphigus vulgaris, when there is no response to it or when significant adverse effects appear as a result of its prolonged use.
AuthorsArmando Nieves Rentería, Jesús G Ochoa Fierro, Verónica A Martínez Ordaz, Miguel A Madero Fernández del Castillo (Affiliation: Departamento de dermatologia, Hospital General de Zona con UMF núm. 16, IMSS, Torreón, Coahuila, México. armando_nieves at yahoo.com.mx)
JournalRevista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) (Rev Alerg Mex) 2005 Jan-Feb Vol. 52 Issue 1 Pg. 39-41 Mexico
Vernacular TitleTratamiento con dosis altas de inmunoglobulina intravenosa en un caso de pénfigo vulgar complicado.
PMID15957471 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Immunoglobulins, Intravenous
Topics
  • Adult
  • Female
  • Humans
  • Immunoglobulins, Intravenous (administration & dosage)
  • Pemphigus (complications, drug therapy)