The effect of neuropeptides on the ERG of the crayfish Orconectes limosus.

Abstract

CCAP (Crustacean Cardioactive Peptide), Proctolin, FMRFamide, Met- and Leu-enkephalin, Substance P, RPCH (red pigment concentrating hormone) and PDH (pigment dispersing hormone) were applied to the isolated retina of the crayfish Orconectes limosus. Changes in light sensitivity, measured as changes of the amplitude of the electroretinogram (ERG) were observed after application of RPCH, PDH and CCAP. RPCH caused an increase of the ERG amplitude to 133% of its reference value whereas PDH and CCAP decreased the amplitude to 78% and 30% respectively. A dose-response curve showed that 10(-9) mol/l CCAP produce a half-maximal effect.

• Authors: G Gaus, H Stieve
• Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences (Z Naturforsch C J Biosci) 1992 Mar-Apr Vol. 47 Issue 3-4 Pg. 300-3 ISSN: 0939-5075 [Print] Germany
• PMID: 1590891 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Neuropeptides

Topics

• Animals
• Astacoidea
• Electroretinography (drug effects)
• Neuropeptides (pharmacology)
• Photic Stimulation
• Retina (drug effects, physiology)
• Structure-Activity Relationship