Abstract |
To examine the efficacy of a low-dose, short-duration creatine monohydrate supplement, 40 physically active men were randomly assigned to either a placebo or creatine supplementation group (6 g of creatine monohydrate per day). Testing occurred before and at the end of 6 days of supplementation. During each testing session, subjects performed three 15-second Wingate anaerobic power tests. No significant (p > 0.05) group or time differences were observed in body mass, peak power, mean power, or total work. In addition, no significant (p > 0.05) differences were observed in peak power, mean power, or total work. However, the change in the rate of fatigue of total work was significantly (p < 0.05) lower in the creatine supplementation group than in the placebo group, indicating a reduced fatigue rate in subjects supplementing with creatine compared with the placebo. Although the results of this study demonstrated reduced fatigue rates in patients during high-intensity sprint intervals, further research is necessary in examining the efficacy of low-dose, short-term creatine supplementation.
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Authors | Jay R Hoffman, Jeffrey R Stout, Michael J Falvo, Jie Kang, Nicholas A Ratamess |
Journal | Journal of strength and conditioning research
(J Strength Cond Res)
Vol. 19
Issue 2
Pg. 260-4
(May 2005)
ISSN: 1064-8011 [Print] United States |
PMID | 15903359
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Anaerobic Threshold
(drug effects, physiology)
- Area Under Curve
- Creatine
(administration & dosage)
- Dietary Supplements
- Dose-Response Relationship, Drug
- Drug Administration Schedule
- Exercise
(physiology)
- Humans
- Male
- Muscle Fatigue
(drug effects, physiology)
- Muscle, Skeletal
(drug effects, physiology)
- Running
(physiology)
- Task Performance and Analysis
- Treatment Outcome
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