[Idiopathic retroperitoneal fibrosis: combined steroid and endourologic treatment].

Abstract

Review of 7 patients with idiopathic retroperitoneal fibrosis (IRF), treated with a combination of corticosteroids (6-methyl-prednisolone) and endourological procedures. The presentation symptom was lumbar pain in all 7 cases. Mean creatinine (Cr) levels were 5.4 mg/dl, with mean erythrocyte sedimentation rate (ESR) of 114. Three (43%) patients were positive to rheumatoid factor (RF) and had raised IgG. Definite diagnosis was achieved in all cases by CAT, including puncture biopsy in 1; all 7 (100%) cases were bilateral. With an average follow-up of 3 years, clinical evolution is satisfactory in all 7 cases. Mean control Cr is 1.2 mg/dl and mean ESR 19. CAT showed disappearance of fibrotic plaque in all cases. One patient relapsed when maintenance therapy was discontinued but responded again to a new therapy course. No steroid therapy-related complications were seen. The association of conservative steroid therapy and endourological procedures is a very low morbidity, sensible alternative in the management of benign retroperitoneal fibrosis where CAT and MNR are the primary diagnostic techniques.

• Authors: F Gómez Veiga, V Chantada Abal, A Sousa Escandón, J Rodríguez García, J Sánchez Rodríguez, M González Martín
• Journal: Actas urologicas espanolas (Actas Urol Esp) Vol. 16 Issue 1 Pg. 17-24 (Jan 1992) ISSN: 0210-4806 [Print] Spain
• Vernacular Title: Fibrosis retroperitoneal idiopática: tratamiento combinado esteroideo y endourológico.
• PMID: 1590069 (Publication Type: English Abstract, Journal Article)

Chemical References

• Methylprednisolone

Topics

• Adult
• Aged
• Algorithms
• Combined Modality Therapy
• Female
• Humans
• Male
• Methylprednisolone (therapeutic use)
• Middle Aged
• Nephrostomy, Percutaneous
• Retroperitoneal Fibrosis (diagnosis, therapy)