The use of growth factors on tendon injuries.

Abstract

Tendon injuries continue to be a vexing clinical problem faced by the upper extremity surgeon. These injuries often lead to disability and dissatisfaction for both the patient and treating physician. Advances throughout the century have focused largely on improvements in surgical techniques and therapy protocols. Recently, attention has been turned to the biologic pathways by which tendons heal and the growth factors involved in this process have been identified. There is great hope that these growth factors may one day be used to treat tendon injuries. This article provides a summary of the use of growth factors on tendon injuries including contemporary research, delivery methods, and future directions in this field.

• Authors: Vishal Mehta, Daniel Mass
• Journal: Journal of hand therapy : official journal of the American Society of Hand Therapists (J Hand Ther) 2005 Apr-Jun Vol. 18 Issue 2 Pg. 87-92; quiz 93 ISSN: 0894-1130 [Print] United States
• PMID: 15891965 (Publication Type: Journal Article, Review)

Chemical References

• Bone Morphogenetic Proteins
• Growth Inhibitors
• Growth Substances

Topics

• Animals
• Bone Morphogenetic Proteins (genetics, therapeutic use)
• Gene Transfer Techniques
• Genetic Therapy
• Growth Inhibitors (therapeutic use)
• Growth Substances (genetics, therapeutic use)
• Humans
• Tendon Injuries (therapy)
• Tissue Adhesions (prevention & control)
• Wound Healing (physiology)