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Eosinophilic fasciitis successfully treated with cyclosporine.

Abstract
We report on a 45-year-old female who developed eosinophilic fasciitis, characterized by scleroderma-like skin indurations, predominantly on the extremities and chest, with joint contractures and intermittent blood eosinophilia. Histologic examination revealed fibrosis of muscle fascia and eosinophilic infiltration. High-dose systemic corticosteroid therapy was ineffective, but cyclosporine treatment led to remission.
AuthorsAleksandra Bukiej, Jerzy Dropiński, Grzegorz Dyduch, Andrzej Szczeklik
JournalClinical rheumatology (Clin Rheumatol) Vol. 24 Issue 6 Pg. 634-6 (Nov 2005) ISSN: 0770-3198 [Print] Germany
PMID15864687 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Immunosuppressive Agents
  • Cyclosporine
Topics
  • Cyclosporine (therapeutic use)
  • Eosinophilia (drug therapy, pathology)
  • Fasciitis (drug therapy, pathology)
  • Female
  • Fibrosis (pathology)
  • Humans
  • Immunosuppressive Agents (therapeutic use)
  • Middle Aged
  • Muscle, Skeletal (pathology)
  • Remission Induction
  • Treatment Outcome

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