HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Repeat keratoplasty for correction of high or irregular postkeratoplasty astigmatism in clear corneal grafts.

AbstractPURPOSE:
To evaluate the functional results of repeat penetrating keratoplasty in clear corneal grafts with high/irregular postkeratoplasty astigmatism.
DESIGN:
Retrospective, longitudinal, single-center, consecutive clinical case series.
METHODS:
We studied 17 eyes (16 keratoconus, 1 Fuchs' dystrophy) of 16 patients (age, 54.9 +/- 12.6 years). They were treated with repeat PK, performed using the 193-nm Zeiss-Meditec MEL-60 excimer laser using round metal masks (diameter, 7.5-8.0 mm), and employing double running sutures. main outcome measures: Subjective refractometry, standard keratometry, and corneal topography (Tomey TMS-1) were used to assess best-corrected visual acuity (BCVA), spherical equivalent (SEQ), keratometric and topographic central corneal power (CP), refractive, keratometric and topographic astigmatism, surface regularity index (SRI), surface asymmetry index (SAI), and potential visual acuity (PVA) preoperatively, before and after first suture removal (1.1 year), and after second suture removal (1.8 years).
RESULTS:
Visual acuity improved significantly (BCVA from 0.2-0.5, P = .04 or better) for all postoperative measurements. CP decreased significantly, but SEQ did not change. All measures of astigmatism and SRI and SAI values showed postoperative improvement with sutures in place; however, astigmatism increased significantly after second suture removal.
CONCLUSIONS:
With all-sutures-in, BCVA and astigmatism improve significantly after repeat PK for high/irregular astigmatism. However, to present significant increase in astigmatism, final suture removal should be postponed as long as possible in such eyes.
AuthorsNóra Szentmáry, Berthold Seitz, Achim Langenbucher, Gottfried O H Naumann
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 139 Issue 5 Pg. 826-30 (May 2005) ISSN: 0002-9394 [Print] United States
PMID15860287 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Adult
  • Aged
  • Astigmatism (physiopathology, surgery)
  • Cornea (physiopathology, surgery)
  • Corneal Topography
  • Female
  • Graft Survival
  • Humans
  • Keratoplasty, Penetrating
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Postoperative Complications (physiopathology, surgery)
  • Reoperation
  • Retrospective Studies
  • Suture Techniques
  • Visual Acuity (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: