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Lethal effects of normeperidine.

Abstract
Normeperidine, having a longer half-life than meperidine, can accumulate faster. Its excitatory neurotoxicity is manifest with administration of multiple meperidine doses or in cases of renal failure. This is a report of the lethal effects of normeperidine in a patient with renal failure who had abused meperidine.
AuthorsK Jiraki
JournalThe American journal of forensic medicine and pathology (Am J Forensic Med Pathol) Vol. 13 Issue 1 Pg. 42-3 (Mar 1992) ISSN: 0195-7910 [Print] United States
PMID1585886 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Cholinesterase Inhibitors
  • Meperidine
  • normeperidine
Topics
  • Adult
  • Cholinesterase Inhibitors (pharmacokinetics, poisoning)
  • Half-Life
  • Humans
  • Kidney Failure, Chronic (complications, etiology)
  • Male
  • Meperidine (administration & dosage, analogs & derivatives, pharmacokinetics, poisoning)
  • Substance-Related Disorders (complications)

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