Acrokeratosis paraneoplastica: Bazex syndrome.

Abstract

Bazex syndrome is a paraneoplastic dermatosis characterized by acral psoriasiform lesions associated with an underlying neoplasm. We present the case of a 64-year-old patient that was diagnosed with squamous cell lung carcinoma after being evaluated for lesions compatible with paraneoplastic acrokeratosis. With a high frequency Bazex syndrome is the earliest marker of an underlying subclinical neoplasm. An early suspicion is of the outmost importance in order to perform a prompt diagnosis of an underlying malignancy. We propose a diagnostic algorithm upon suspicion of acrokeratosis paraneoplastica and review the pathogenesis of this entity.

• Authors: M Valdivielso, I Longo, R Suárez, M Huerta, P Lázaro
• Journal: Journal of the European Academy of Dermatology and Venereology : JEADV (J Eur Acad Dermatol Venereol) Vol. 19 Issue 3 Pg. 340-4 (May 2005) ISSN: 0926-9959 [Print] England
• PMID: 15857461 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Carcinoma, Squamous Cell (complications)
• Humans
• Keratosis (diagnosis, pathology)
• Lung Neoplasms (complications)
• Male
• Middle Aged
• Paraneoplastic Syndromes (diagnosis, pathology)
• Syndrome