| Abstract | A 42-year-old woman with multiple organ metastases from breast cancer was successfully treated with 5'-deoxy-5-fluorouridine (5'-DFUR) and hormonal therapy (leuprorelin+tamoxifen). She underwent radical mastectomy for advanced left breast cancer in June 1998. In September 2000, she was treated with docetaxel for multiple lung metastases, and the lesions were diagnosed as in complete remission. In June 2001, she received radiation for bone metastasis in left femoral and received a resection of subcutaneous metastases in the face. Then she received 2 courses of paclitaxel. In May 2002, she had multiple lung metastases, right adrenal metastasis, tumor thrombus in the inferior vena cava and multiple bone metastases, and was treated with cycrophosphamide, epirubicin, and 5-FU, however, they were abandoned due to severe leucopenia. Therefore, 600 mg/day of 5'-DFUR was administered from December 2002. The lesions of lung and adrenal decreased extendedly in March 2003. She was diagnosed as being in CR in March 2004, and this condition has continued to the present. |
| Authors | Eiji Sakamoto, Hiroshi Hasegawa, Shunichiro Komatsu, Takashi Hiromatsu, Keita Itazu, Tomotake Tabata, Kiyotaka Kawai, Yasuyuki Fukami
(Affiliation: Dept of Surgery, Nagoya Daini Red Cross Hospital.)
|
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 32
Issue 4
Pg. 539-42
(Apr 2005)
ISSN: 0385-0684 Japan |
| PMID | 15853224
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Chemical References |
- Antineoplastic Agents, Hormonal
- Tamoxifen
- doxifluridine
- Cyclophosphamide
- Floxuridine
- Leuprolide
- Epirubicin
|
| Topics |
- Adult
- Antineoplastic Agents, Hormonal
(administration & dosage)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Bone Neoplasms
(drug therapy, secondary)
- Breast Neoplasms
(drug therapy, pathology, surgery)
- Carcinoma, Papillary
(drug therapy, secondary, surgery)
- Combined Modality Therapy
- Cyclophosphamide
(administration & dosage)
- Drug Administration Schedule
- Epirubicin
(administration & dosage)
- Female
- Floxuridine
(administration & dosage)
- Follow-Up Studies
- Humans
- Leuprolide
(administration & dosage)
- Lung Neoplasms
(drug therapy, secondary)
- Mastectomy, Radical
- Neoplasm Circulating Cells
(pathology)
- Tamoxifen
(administration & dosage)
- Vena Cava, Inferior
(pathology)
|
