Abstract |
It is assumed that skin is protected against sunburn by melanin. In patients with vitiligo, there are white patches in the normal pigmented skin. We noticed that there is a difference in burning capacity of these white patches between people with different skin types. With UVB 311 nm lamps, we irradiated both lesional and non-lesional skin with increasing doses in 33 patients with vitiligo, divided into 5 groups according to skin type (II-VI). Twenty-four hours later we assessed the minimal erythema dose and found a correlation between skin type and UV sensitivity in both lesional skin and normal skin. We suggest that there must be a protection mechanism, other than that offered by melanin pigmentation. The antioxidant status may play a role in this phenomenon.
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Authors | Anne-Lou D B Caron-Schreinemachers, Melanie M Kingswijk, Jan D Bos, Wiete Westerhof |
Journal | Acta dermato-venereologica
(Acta Derm Venereol)
Vol. 85
Issue 1
Pg. 24-6
( 2005)
ISSN: 0001-5555 [Print] Sweden |
PMID | 15848986
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Adult
- Dose-Response Relationship, Radiation
- Erythema
(etiology, prevention & control)
- Female
- Humans
- Male
- Middle Aged
- Radiation Tolerance
- Skin Pigmentation
(radiation effects)
- Ultraviolet Rays
(adverse effects)
- Vitiligo
(complications)
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