Zonisamide for absence seizures.

Abstract

This chart review investigated the efficacy and safety of zonisamide in 45 patients aged < or = 18 years with absence seizures. Of these patients, 23 (51.1%) achieved freedom from absence seizures. Two patients discontinued zonisamide, 1 for increased seizures and 1 for sleepiness and inefficacy. These data support the efficacy of zonisamide in treating absence seizures.

• Authors: Angus Wilfong, Rebecca Schultz
• Journal: Epilepsy research (Epilepsy Res) 2005 Mar-Apr Vol. 64 Issue 1-2 Pg. 31-4 ISSN: 0920-1211 [Print] Netherlands
• PMID: 15847848 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Anticonvulsants
• Isoxazoles
• Zonisamide

Topics

• Adolescent
• Anticonvulsants (therapeutic use)
• Body Weight (drug effects)
• Child
• Child, Preschool
• Clinical Trials as Topic
• Epilepsy, Absence (drug therapy)
• Female
• Humans
• Isoxazoles (therapeutic use)
• Male
• Treatment Outcome
• Zonisamide