Correlation of serum magnesium with dyslipidemia in maintenance hemodialysis patients.

• Abstract: One of the factors involved in accelerated atherosclerosis in hemodialysis patients is dyslipidemia. In this study we considered factors involved in intensification of dyslipidemia in hemodialysis patients. This study was done on 36 maintenance hemodialysis patients. Serum lipoprotein (a), Triglyceride, Cholesterol, HDL-C,LDL-C and also serum Intact parathormone(iPTH), Calcium, Phosphorus, Magnesium were measured. In statistical analysis there was not any correlation between serum lipids and iPTH. There was not correlation between serum calcium with serum lipids (p > 0.05). There was not correlation between CaxP product with serum lipids (p > 0.05). There was a positive correlation between serum Magnesium and Lipoprotein(a) (P < 0.05) and also positive correlation between serum magnesium with triglyceride level (P < 0.05) was seen too. Magnesium doesn't increase the lipoprotein synthesis. It may involve in the regulation of some enzymes responsible for lipoprotein synthesis. Correlation of serum magnesium with serum triglycerides can be due to changes in hepatic triglyceride metabolism. Lipoprotein(a) is a non traditional factor of premature atherosclerosis, its association with serum magnesium needs more attention in hemodialysis patients.
• Authors: Hamid Nasri, Azar Baradaran (Affiliation: Shahrekord University of Medical Sciences, Hajar Medical, Educational and Therapeutic Center, Section of Hemodialysis, Shahrekord, Iran. hamidnasri at skums.ac.ir)
• Journal: Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové (Acta Medica (Hradec Kralove)) Vol. 47 Issue 4 Pg. 263-5 ( 2004) ISSN: 1211-4286 [Print] Czech Republic
• PMID: 15841906 (Publication Type: Journal Article)

Chemical References

• Lipoprotein(a)
• Triglycerides
• Magnesium

Topics

• Female
• Humans
• Hyperlipidemias (blood, etiology)
• Lipoprotein(a) (blood)
• Magnesium (blood)
• Male
• Middle Aged
• Renal Dialysis (adverse effects)
• Triglycerides (blood)