Abstract | BACKGROUND: Various methods have been applied for the treatment of periimplantitis lesions. It has been reported that the procedures used have been effective in eliminating the inflammatory lesion but that re-osseointegration to the once-contaminated implant surface has been difficult or impossible to achieve. PURPOSE: MATERIALS AND METHODS: Three dental implants (ITI Dental Implant System, Straumann AG, Waldenburg, Switzerland) were placed in each side of the edentulous mandible of four beagle dogs. Implants with a turned surface and implants with a sand-blasted large-grit acid-etched (SLA) surface (SLA, Straumann AG, Waldenburg, Switzerland) were used. Experimental periimplantitis was induced during 3 months. Five weeks later each animal received tablets of amoxicillin and metronidazole for a period of 17 days. Three days after the start of the antibiotic treatment, full-thickness flaps were elevated, and the granulation tissue in the bone craters was removed. In the two anterior implant sites in both sides of the mandible, a combination of CO2 laser therapy and application of a water solution of hydrogen peroxide was used. The implant in the posterior site of each quadrant was cleaned with cotton pellets soaked in saline. Biopsy specimens were obtained 6 months later. RESULTS: The amount of re-osseointegration was 21% and 82% at laser-treated turned-surface implants and SLA implants, respectively, and 22% and 84% at saline-treated turned-surface implants and SLA implants, respectively. CONCLUSIONS: The present study demonstrated the following: (1) a combination of systemic antibiotics and local curettage and debridement resulted in the resolution of experimentally induced periimplantitis lesions; (2) at implants with a turned surface, a small amount of re-osseointegration was observed at the base of the bone defects whereas a considerable amount of re-osseointegration occurred at implants with an SLA surface; and (3) the use of CO2 laser and hydrogen peroxide during surgical therapy had no apparent effect on bone formation and re-osseointegration.
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Authors | Leif G Persson, Jafaar Mouhyi, Tord Berglundh, Lars Sennerby, Jan Lindhe |
Journal | Clinical implant dentistry and related research
(Clin Implant Dent Relat Res)
Vol. 6
Issue 4
Pg. 230-8
( 2004)
ISSN: 1523-0899 [Print] United States |
PMID | 15841583
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Bacterial Agents
- Dental Implants
- Oxidants
- Carbon Dioxide
- Hydrogen Peroxide
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Topics |
- Animals
- Anti-Bacterial Agents
(therapeutic use)
- Carbon Dioxide
- Dental Implantation, Endosseous
(adverse effects)
- Dental Implants
(adverse effects)
- Dogs
- Hydrogen Peroxide
(therapeutic use)
- Implants, Experimental
- Laser Therapy
- Osseointegration
- Oxidants
(therapeutic use)
- Periodontitis
(etiology, surgery, therapy)
- Subgingival Curettage
- Surface Properties
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