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Mutation in cGMP-dependent protein kinase II causes dwarfism in a rat mutant KMI through uncoupling of proliferation and differentiation of chondrocytes.

AuthorsHirotaka Chikuda, Fumitaka Kugimiya, Kazuto Hoshi, Toshiyuki Ikeda, Toru Ogasawara, Satoru Kamekura, Naoshi Ogata, Kozo Nakamura, Ung-Il Chung, Hiroshi Kawaguchi
JournalJournal of bone and mineral metabolism (J Bone Miner Metab) Vol. 23 Issue 3 Pg. 200-4 ( 2005) ISSN: 0914-8779 [Print] Japan
PMID15838621 (Publication Type: Journal Article, Review)
Chemical References
  • High Mobility Group Proteins
  • SOX9 Transcription Factor
  • Transcription Factors
  • Cyclic GMP-Dependent Protein Kinase Type II
  • Cyclic GMP-Dependent Protein Kinases
  • Prkg2 protein, rat
Topics
  • Animals
  • Bone Development
  • Cell Differentiation
  • Cell Proliferation
  • Chondrocytes (pathology)
  • Cyclic GMP-Dependent Protein Kinase Type II
  • Cyclic GMP-Dependent Protein Kinases (genetics)
  • Dwarfism (genetics, pathology)
  • Growth Plate (pathology)
  • High Mobility Group Proteins (genetics)
  • Mutation
  • Rats
  • SOX9 Transcription Factor
  • Signal Transduction
  • Transcription Factors (genetics)

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