Returning hypertrophy after surgery in a patient with hypertrophic cardiomyopathy caused by a myosin-binding protein C mutation.

Abstract

We report a 13-year follow-up of a patient who underwent both myectomy and septal ablation due to hypertrophic cardiomyopathy caused by a cardiac myosin-binding protein C gene mutation. After myectomy the patient again developed significant septal hypertrophy at the operated septal area with a need for a second interventional therapy. This exceptional case underscores the remarkable ability of the heart muscle to show a continuous hypertrophic process over many years.

• Authors: Zhyldyz Kabaeva, Andreas Perrot, Bernhard Pilz, Jeanette Schulz-Menger, Friedrich-Wilhelm Mohr, Rainer Dietz, Karl Josef Osterziel
• Journal: International journal of cardiology (Int J Cardiol) Vol. 100 Issue 2 Pg. 343-5 (Apr 20 2005) ISSN: 0167-5273 [Print] Netherlands
• PMID: 15823648 (Publication Type: Case Reports, Letter)

Chemical References

• Carrier Proteins
• myosin-binding protein C

Topics

• Adult
• Cardiomyopathy, Hypertrophic, Familial (genetics, surgery)
• Carrier Proteins (genetics)
• Humans
• Male
• Recurrence