Abstract | PURPOSE: We assayed whether high serum carotenoids and antioxidative substances decrease the risk of urothelial cancer in a case-control study nested in a community based cohort in Japan, that is the Japan Collaborative Cohort Study. MATERIALS AND METHODS: Information on subject life-styles and serum were collected in 1988 to 1990 and subjects were followed as late as 1999. Individuals who had or died of urothelial cancer and controls were matched for study area, sex and age. Serum was stored at -80C and analyzed in 2003. Of 14,097 male and 25,662 female subjects 40 to 79 years old there were 42 cases, which were matched to 124 controls. RESULTS: CONCLUSIONS:
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Authors | Kotaro Ozasa, Yoshinori Ito, Koji Suzuki, Yoshiyuki Watanabe, Kyohei Hayashi, Kazuya Mikami, Masahiro Nakao, Tsuneharu Miki, Mitsuru Mori, Fumio Sakauchi, Masakazu Washio, Tatsuhiko Kubo, Kenji Wakai, Akiko Tamakoshi, Japan Collaborative Cohort Study Group |
Journal | The Journal of urology
(J Urol)
Vol. 173
Issue 5
Pg. 1502-6
(May 2005)
ISSN: 0022-5347 [Print] United States |
PMID | 15821468
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Aged
- Antioxidants
(analysis)
- Carotenoids
(blood)
- Case-Control Studies
- Female
- Humans
- Japan
- Male
- Risk
- Urologic Neoplasms
(blood)
- Urothelium
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