Normal birth after transfer of cryopreserved human embryos generated by microinjection of cryopreserved testicular spermatozoa into cryopreserved human oocytes.

Abstract

OBJECTIVE:

To report the first birth after transfer of cryopreserved embryos generated by intracytoplasmic sperm injection of cryopreserved testicular spermatozoa into cryopreserved human oocytes.

DESIGN:

Case report.

SETTING:

Tertiary center for reproductive technology.

PATIENT(S):

A 36-year-old woman with primary infertility of 3 years' duration and a 37-year-old man with congenital bilateral absence of the vas deferens.

INTERVENTION(S):

Cryopreservation of human embryos after oocytes and sperm thawing.

MAIN OUTCOME MEASURE(S):

Live birth.

RESULT(S):

A healthy, normal female infant with a birth weight of 2,950 g was born by cesarean section at 38 weeks' gestation, with normal 6-month follow-up.

CONCLUSION(S):

Embryo cryopreservation can lead to successful results, even with the use of cryopreserved gametes.

• Authors: Paolo Emanuele Levi Setti, Elena Albani, Paola Vittoria Novara, Amalia Cesana, Silvia Bianchi, Luciano Negri
• Journal: Fertility and sterility (Fertil Steril) Vol. 83 Issue 4 Pg. 1041 (Apr 2005) ISSN: 1556-5653 [Electronic] United States
• PMID: 15820821 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Birth Weight
• Cesarean Section
• Cryopreservation (methods)
• Embryo Transfer
• Female
• Fertilization in Vitro (methods)
• Follow-Up Studies
• Gestational Age
• Humans
• Infant, Newborn
• Infertility, Female (therapy)
• Male
• Microinjections
• Oocytes (physiology)
• Pregnancy
• Pregnancy Outcome (epidemiology)
• Sperm-Ovum Interactions (physiology)
• Spermatozoa (physiology, transplantation)
• Vas Deferens (abnormalities, physiology)