Abstract | BACKGROUND: METHODS: RESULTS: Significant decreases in streptococcal infections during the study year were found with a mean of .1 (.3 SD) per subject, compared to the baseline year with 1.9 (1.2 SD) in the penicillin group and 2.4 (1.1 SD) in the azithromycin group [p<.01]. Significant decreases in neuropsychiatric exacerbations during the study year were also found with a mean of .5 (.5 SD) per subject in the penicillin group and .8 (.6 SD) in the azithromycin group, compared to the baseline year with 2.0 (.9 SD) in the penicillin group and 1.8 (.6 SD) in the azithromycin group [p<.01]. CONCLUSIONS:
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Authors | Lisa A Snider, Lorraine Lougee, Marcia Slattery, Paul Grant, Susan E Swedo |
Journal | Biological psychiatry
(Biol Psychiatry)
Vol. 57
Issue 7
Pg. 788-92
(Apr 01 2005)
ISSN: 0006-3223 [Print] United States |
PMID | 15820236
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Antibiotic Prophylaxis
- Azithromycin
(therapeutic use)
- Child
- Child, Preschool
- Double-Blind Method
- Female
- Follow-Up Studies
- Humans
- Male
- Obsessive-Compulsive Disorder
(drug therapy, microbiology)
- Penicillins
(therapeutic use)
- Psychiatric Status Rating Scales
- Retrospective Studies
- Streptococcal Infections
(complications, drug therapy, microbiology)
- Treatment Outcome
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