Bilateral anterior granulomatous uveitis associated with cutaneous Rosai-Dorfman disease.

Abstract

BACKGROUND:

Rosai-Dorfman disease (RDD) is a benign, rare, histiocytic disorder of unknown etiology. We describe the case of a 61-year-old woman who presented to the ophthalmology clinic with bilateral granulomatous anterior uveitis.

METHODS:

The uveitis was controlled on topical prednisolone acetate 1%. One month after presentation, she developed generalized macules and papules, and dermatologic and systemic evaluations were performed.

RESULTS:

On the basis of skin biopsy, purely cutaneous RDD was established.

CONCLUSION:

Anterior granulomatous uveitis may be the presenting sign of cutaneous RDD. Consultation is necessary for accurate diagnosis.

• Authors: Juan G Gaviria, Daniel A Johnson, Marsha C Kinney, Liana H Proffer, Jacqueline M Losi-Sasaki, Eric W Kraus
• Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (Graefes Arch Clin Exp Ophthalmol) Vol. 243 Issue 3 Pg. 281-4 (Mar 2005) ISSN: 0721-832X [Print] Germany
• PMID: 15806376 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)

Topics

• Female
• Granuloma (etiology)
• Histiocytosis, Sinus (complications, pathology)
• Humans
• Middle Aged
• Skin Diseases (complications, pathology)
• Uveal Diseases (etiology)
• Uveitis, Anterior (etiology)