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Correction of myopia of 7 to 24 diopters with the Artisan phakic intraocular lens: two-year follow-up.

AbstractPURPOSE:
To evaluate the safety and efficacy of the iris claw phakic intraocular lens (Artisan; Ophtec BV, Groningen, The Netherlands) in patients with high myopia.
METHODS:
Between May 1999 and July 2001, 93 Artisan phakic intraocular lenses (IOLs) were implanted in 60 patients affected by high myopia. All patients underwent 24-month follow-up. The power of the lenses ranged from -7.5 to -22.0 diopters (D). Patients were divided into two groups: group 1 (68 eyes), myopia -6.75 to -15.50 D (SE), and group 2 (25 eyes), myopia -16.0 to -23.0 D (SE). Pre- and postoperative patient evaluation included manifest and cycloplegic refractions, uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), endothelial cell count, intraocular pressure, complication rate, safety, and efficacy.
RESULTS:
At 4 months, 83.8% (57/68) (group 1, myopia -6.75 to -15.50 D) and 68% (17/25) (group 2, myopia -16.0 to -23.0 D) of eyes achieved UCVA of > or =20/40. The BSCVA remained the same or improved in 100% of eyes. After 4 months, 69.1% (47/68) of eyes in group 1 and 52% (13/25) of eyes in group 2 were within +/-1.00 D of the desired refraction; the mean refraction was stable between 4 and 24 months. Of the intraoperative complications, 69.2% were observed in the first 25 lenses implanted; postoperative complications included iris atrophy in 11.8% (11/93), lens decentration in 5.4% (5/93), and night glare in 6.4% (6/93) of eyes. No IOLs were removed. Mean endothelial cell loss was 2.8% at 4 months, 3.9% at 12 months, and 5.4% at 24 months.
CONCLUSIONS:
Our results regarding implantation of the Artisan phakic IOL confirm that these lenses are safe and effective for the correction of high myopia, with a stable refractive outcome but with a higher than normal rate of endothelial cell loss during 2-year follow-up.
AuthorsStefano Benedetti, Virna Casamenti, Lucio Marcaccio, Carlo Brogioni, Vincenzo Assetto
JournalJournal of refractive surgery (Thorofare, N.J. : 1995) (J Refract Surg) 2005 Mar-Apr Vol. 21 Issue 2 Pg. 116-26 ISSN: 1081-597X [Print] United States
PMID15796215 (Publication Type: Comparative Study, Journal Article)
Topics
  • Adult
  • Endothelium, Corneal (pathology)
  • Female
  • Follow-Up Studies
  • Humans
  • Lens Implantation, Intraocular (methods)
  • Lens, Crystalline (physiology)
  • Lenses, Intraocular
  • Male
  • Middle Aged
  • Myopia (physiopathology, surgery)
  • Prosthesis Design
  • Refraction, Ocular (physiology)
  • Retrospective Studies
  • Safety
  • Treatment Outcome
  • Visual Acuity

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