[An effect of antioxidant drugs on symptoms of sensomotor polyneuropathy and affective disorders in patients with diabetes mellitus].

Abstract

An effect of 3-oxypiridine and succinic acid derivates--emoxipine, reamberin and mexidole--on severity of clinical symptoms of distal sensomotor polyneuropathy, anxiety and depression was studied in 120 patients with diabetes mellitus with syndrome of diabetic foot. These medications were used in addition to basic antidiabetic therapy. After 14 days of the treatment an equally pronounced decrease of integral index of "negative" neurological symptoms and reduction of anxiety-depressive disorders were detected.

• Authors: I A Volchegorskiĭ, M G Moskvicheva, E N Chashchina
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 105 Issue 2 Pg. 41-5 ( 2005) ISSN: 1997-7298 [Print] Russia (Federation)
• PMID: 15792141 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Antioxidants
• Hypoglycemic Agents
• Picolines
• Psychotropic Drugs
• emoxypine succinate
• 6-methyl-2-ethyl-3-hydroxypyridine

Topics

• Aged
• Antioxidants (therapeutic use)
• Anxiety Disorders (complications, diagnosis, drug therapy)
• Data Interpretation, Statistical
• Depressive Disorder (complications, diagnosis, drug therapy)
• Diabetes Mellitus, Type 1 (complications)
• Diabetes Mellitus, Type 2 (complications)
• Diabetic Neuropathies (complications, diagnosis, drug therapy)
• Female
• Follow-Up Studies
• Humans
• Hypoglycemic Agents (administration & dosage, therapeutic use)
• Male
• Middle Aged
• Picolines (administration & dosage, therapeutic use)
• Psychotropic Drugs (therapeutic use)
• Time Factors
• Treatment Outcome