| Abstract | Estrogen deficiency and low calcium intake are important contributors to the development of osteoporosis in postmenopausal women. Hormone replacement therapy (HRT) has been shown to be effective prevention of postmenopausal bone loss. Due to a potent action of anti-bone-resorption, HRT causes a secondary elevation of serum PTH and correction of calcium imbalance is mandatory for long-term HRT. Administration of vitamin D in combination with HRT is rational and is shown to be more effective than HRT alone. |
| Authors | Hideki Mizunuma
(Affiliation: Department of Obst. and Gynecol Hirosaki University School of Medicine.)
|
| Journal | Clinical calcium
(Clin Calcium)
Vol. 12
Issue 7
Pg. 944-8
(Jul 2002)
ISSN: 0917-5857 Japan |
| PMID | 15775386
(Publication Type: English Abstract, Journal Article)
|
