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[The possible novel treatment of achondroplasia, C-type natriuretic peptide (CNP)].

Abstract
C-type natiruetic peptide (CNP) showed a potent effect on the elongation of the tibial organ culture system. CNP also corrected the dwarfing phenotype of the CNP knockout mice. These results suggest that CNP is the novel promoter of the endochondral ossification, and that CNP/GC-B activation is possible target of the treatment of the achondroplasia.
AuthorsYasato Komatsu, Akihiro Yasoda, Hideki Chusho, Kazuwa Nakao
JournalClinical calcium (Clin Calcium) Vol. 13 Issue 12 Pg. 1578-81 (Dec 2003) ISSN: 0917-5857 [Print] Japan
PMID15775246 (Publication Type: English Abstract, Journal Article)

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